Targeted therapy with imatinib has transformed the treatment of chronic myeloid leukemia (CML). Unlike CML, chronic lymphocytic leukemia (CLL) lacks a common genetic aberration but does demonstrate ...
Phosphoinositide 3-kinases (PI3Ks) are involved in many vital cell functions and their dysregulation has been implicated in the pathology of various disorders. Pharmacological and genetic studies have ...
DUBLIN--(BUSINESS WIRE)--The "Copiktra" report has been added to ResearchAndMarkets.com's offering. Copiktra (duvelisib; Verastem/Yakult Honsha) is a highly selective small molecule inhibitor of the ...
Myriad of Groups Are Working on the Latest Hot Target and Most Are Optimistic About Its Potential Although the term “signal transduction” was coined back in 1972, cell-signaling switches have only ...
INDIANAPOLIS, April 5, 2011 (GLOBE NEWSWIRE) -- Semafore Pharmaceuticals today announced encouraging preclinical results for its lead product candidate, SF1126, in certain B-cell malignancies. The ...
Researchers from the 'Angiogenesis signaling pathways' research group of the Institute of Biomedical Investigation of Bellvitge (IDIBELL), led by Dr. Mariona Graupera, have unveiled the potential ...
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